Calculated panel reactive antibodies (CPRA) is a sensitization measure used to classify and prioritize transplant candidates in different kidney transplant allocation systems. CPRA is based on identification of HLA unacceptable on potential organ donors making a transplant candidate ineligible for transplantation.
Here, we present a CPRA online estimator based on HLA allelic and haplotypic frequencies from Portuguese donors. We also compare the values we obtained from our CPRA estimator (Portuguese [PT]-CPRA) against CPRA values obtained from: Eurotransplant virtual PRA calculator (ET-CPRA); Canadian CPRA calculator (Canadian [CN]-CPRA) and Organ Procurement and Transplantation Network CPRA calculator (United States [US]-CPRA).
CD3 |
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3B1-01MG | ImmunoStep | 100 test | EUR 340.8 |
CD3 |
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3CFB1-100T | ImmunoStep | 100 test | EUR 465.6 |
CD3 |
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3CFB2-100T | ImmunoStep | 100 test | EUR 465.6 |
CD3 |
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3DY1-100T | ImmunoStep | 100 test | EUR 418.8 |
CD3 |
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3F1-100T | ImmunoStep | 100 test | EUR 356.4 |
CD3 |
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3PC2-100T | ImmunoStep | 100 test | EUR 730.8 |
CD3 |
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3PE1-100T | ImmunoStep | 100 test | EUR 418.8 |
CD3 |
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3PP1-100T | ImmunoStep | 100 test | EUR 418.8 |
CD3 |
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3PP5.5-100T | ImmunoStep | 100 test | EUR 465.6 |
CD3 |
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3PU1-01MG | ImmunoStep | 0,1 mg | EUR 262.8 |
CD3 |
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ABF5405 | Lifescience Market | 100 ug | EUR 525.6 |
CD3 |
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ABF5425 | Lifescience Market | 100 ug | EUR 525.6 |
CD3 |
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ant-144 | ProSpec Tany | 0.5mg | EUR 275 |
Description: Mouse Anti Human CD3 |
CD3 |
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ant-175 | ProSpec Tany | 0.5mg | EUR 275 |
Description: Rat Anti Mouse CD3 |
CD3/ Rat CD3 ELISA Kit |
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ELA-E1872r | Lifescience Market | 96 Tests | EUR 1063.2 |
CD3 Gamma (CD3 gamma) Antibody |
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abx231460-100ug | Abbexa | 100 ug | EUR 577.2 |
CD3 (ABT-CD3) Mouse mAb |
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E2252836 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
CD3/CD19 |
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3F119PE1-50T | ImmunoStep | 50 test | EUR 420.36 |
CD3/CD4 |
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3F14PE1-50T | ImmunoStep | 50 test | EUR 420.36 |
CD3/CD8 |
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3F18PE1-50T | ImmunoStep | 50 test | EUR 420.36 |
CD3 FITC |
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ant-137 | ProSpec Tany | 0.5mg | EUR 275 |
Description: Mouse Anti Human CD3-FITC |
CD3 gamma |
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PR27317 | Neuromics | 5 ug | EUR 229.2 |
CD3 Biotin |
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ant-138 | ProSpec Tany | 0.5mg | EUR 275 |
Description: Mouse Anti Human CD3-Biotinylated |
CD3 epsilon |
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E8ER80501 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
CD3 epsilon |
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E8ET1607-29 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
CD3 Antibody |
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abx140459-100tests | Abbexa | 100 tests | EUR 577.2 |
CD3 Antibody |
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abx140490-100tests | Abbexa | 100 tests | EUR 510 |
CD3 Antibody |
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abx140491-100tests | Abbexa | 100 tests | EUR 577.2 |
CD3 antibody |
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10-Z03A | Fitzgerald | 800 ug | EUR 296.4 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10-2488 | Fitzgerald | 100 ug | EUR 289.2 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10R-1790 | Fitzgerald | 100 ul | EUR 289.2 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10R-6328 | Fitzgerald | 100 ug | EUR 230.4 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10R-6329 | Fitzgerald | 100 ug | EUR 171.6 |
Description: Armenian Hamster monoclonal CD3 antibody |
CD3 antibody |
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10R-6330 | Fitzgerald | 100 ug | EUR 230.4 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10R-6331 | Fitzgerald | 100 ug | EUR 262.8 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10R-7748 | Fitzgerald | 500 ug | EUR 678 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10R-7770 | Fitzgerald | 500 ug | EUR 678 |
Description: Rat monoclonal CD3 antibody |
CD3 antibody |
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10R-7833 | Fitzgerald | 100 ug | EUR 386.4 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10R-CD3aHU | Fitzgerald | 100 ul | EUR 571.2 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10R-CD3fCKp | Fitzgerald | 500 ug | EUR 483.6 |
Description: Mouse monoclonal CD3 antibody |
CD3 antibody |
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10R-CD3gHU | Fitzgerald | 100 ug | EUR 198 |
Description: Mouse monoclonal CD3 antibody |
CD3 Antibody |
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F52219-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 140.25 |
Description: The CD3 complex mediates signal transduction. |
CD3 Antibody |
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F52219-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 330.65 |
Description: The CD3 complex mediates signal transduction. |
CD3 Antibody |
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E10-20024 | EnoGene | 100μg/100μl | EUR 225 |
Description: Available in various conjugation types. |
CD3 Antibody |
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E3M00016 | EnoGene | 200ul | EUR 275 |
Description: Available in various conjugation types. |
CD3 antibody |
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10R-CD3aHUS | Fitzgerald | 200 ug | EUR 351 |
Description: Mouse monoclonal CD3 antibody |
CD3 Antibody |
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R30014 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: The alpha-beta heterodimeric T-cell antigen receptor binds antigen in association with major histocompatibility complex proteins on host cell surfaces. These 2 disulfide-linked glycoproteins, TCRA and TCRB are associated on T-cell surfaces with a complex of proteins called CD3(formerly T3). Human CD3 consists of at least 4 proteins: gamma, delta, epsilon, and zeta. The CD3-gamma/CD3-delta gene pair is within 300 kb of the CD3-epsilon gene and therefore these genes form a tightly linked cluster on 11q23. The clustering may be significant in terms of their simultaneous activations during T-cell development. |
CD3 Antibody |
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V2379-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. |
CD3 Antibody |
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V2379-20UG | NSJ Bioreagents | 20 ug | EUR 153.3 |
Description: CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. |
CD3 Antibody |
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V2379SAF-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. |
CD3 Antibody |
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V2380-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: The CD3 complex mediates signal transduction. [UniProt] |
CD3 Antibody |
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V2380-20UG | NSJ Bioreagents | 20 ug | EUR 153.3 |
Description: The CD3 complex mediates signal transduction. [UniProt] |
CD3 Antibody |
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V2380SAF-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
Description: The CD3 complex mediates signal transduction. [UniProt] |
CD3 Antibody |
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DF6594 | Affinity Biosciences | 100ul | EUR 280 |
Description: Human,Mouse,Rat |
CD3 Antibody |
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DF6594-100ul | Affinity Biosciences | 100ul | EUR 280 |
CD3 Antibody |
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DF6594-200ul | Affinity Biosciences | 200ul | EUR 350 |
CD3, Antibody |
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GWB-299497 | GenWay Biotech | 1 ml | Ask for price |
CD3 Antibody |
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GWB-256038 | GenWay Biotech | 0.5 ml | Ask for price |
CD3, Antibody |
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GWB-B59FE3 | GenWay Biotech | 0.2 mg | Ask for price |
CD3 Antibody |
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GWB-4E4A74 | GenWay Biotech | 0.1 mg | Ask for price |
CD3 Antibody |
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GWB-515925 | GenWay Biotech | 0.1 mg | Ask for price |
CD3 Antibody |
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GWB-48F4B7 | GenWay Biotech | 0.1 mg | Ask for price |
CD3 Antibody |
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GWB-8AAC5E | GenWay Biotech | 0.1 mg | Ask for price |
CD3, Antibody |
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GWB-B0EACA | GenWay Biotech | 0.1 ml | Ask for price |
CD3, Antibody |
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GWB-38C7C0 | GenWay Biotech | 7 ml | Ask for price |
CD3 Antibody |
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GWB-440824 | GenWay Biotech | 0.02 mg | Ask for price |
CD3 Antibody |
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GWB-45716C | GenWay Biotech | 2 ml | Ask for price |
CD3 Antibody |
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GWB-79D159 | GenWay Biotech | 0.1 mg | Ask for price |
CD3 Antibody |
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GWB-7A0B10 | GenWay Biotech | 0.05 mg | Ask for price |
CD3, Antibody |
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GWB-8E9B3B | GenWay Biotech | 7 ml | Ask for price |
CD3, Antibody |
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GWB-C8D63B | GenWay Biotech | 0.1 ml | Ask for price |
CD3, Antibody |
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GWB-FD262E | GenWay Biotech | 1 ml | Ask for price |
CD3 Antibody |
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GWB-AB964C | GenWay Biotech | 0.2 mg | Ask for price |
CD3 Antibody |
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GWB-AC61DB | GenWay Biotech | 0.2 mg | Ask for price |
CD3, Antibody |
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GWB-DC7BEB | GenWay Biotech | 0.1 ml | Ask for price |
CD3 Antibody |
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GWB-Q01400 | GenWay Biotech | 0.2 mg | Ask for price |
CD3 Antibody |
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GWB-Q01401 | GenWay Biotech | 25 ug | Ask for price |
CD3 Antibody |
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GWB-EEFBE8 | GenWay Biotech | 0.2 mg | Ask for price |
CD3 Antibody |
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GWB-F12953 | GenWay Biotech | 0.2 mg | Ask for price |
CD3 epsilon&CD3 gamma Heterodimer Recombinant Protein |
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11-551 | ProSci | 0.05 mg | EUR 714.3 |
Description: T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. |
CD3/CD19/CD45 |
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3F119PE145PP1-50T | ImmunoStep | 50 test | EUR 574.8 |
CD3/CD4/CD45 |
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3F14PE145PC3-50T | ImmunoStep | 50 test | EUR 677.76 |
CD3/CD4/CD45 |
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3F14PE45PP1-50T | ImmunoStep | 50 test | EUR 574.8 |
CD3/CD8/CD45 |
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3F18PE145PP1-50T | ImmunoStep | 50 test | EUR 626.28 |
CD3/CD16+56 |
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3F11656PE-50T | ImmunoStep | 50 test | EUR 420.36 |
CD4/CD8/CD3 |
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4F18PE13PC2-50T | ImmunoStep | 50 test | EUR 660.6 |
CD4/CD8/CD3 |
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4F8PE13PP1-50T | ImmunoStep | 50 test | EUR 626.28 |
Phalaenopsine Is |
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T124877-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Phalaenopsine Is |
Phalaenopsine Is |
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T124877-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Phalaenopsine Is |
Phalaenopsine Is |
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T124877-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Phalaenopsine Is |
Phalaenopsine Is |
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T124877-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Phalaenopsine Is |
Phalaenopsine Is |
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T124877-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Phalaenopsine Is |
IS-159 |
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T27628-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: IS-159 |
IS-159 |
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T27628-1g | TargetMol Chemicals | 1g | Ask for price |
Description: IS-159 |
IS-159 |
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T27628-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: IS-159 |
IS-159 |
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T27628-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: IS-159 |
IS-159 |
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T27628-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: IS-159 |
HLA-DR/CD3 |
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HLADRF3PE1-50T | ImmunoStep | 50 test | EUR 420.36 |
CD3+ T Cells |
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ABC-SC0140T | AcceGen | 1 vial | Ask for price |
Description: Purified CD3+ are isolated from PBMC, include CD4+ and CD8+ subsets. |
CD3 Mouse mAb |
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E2620243 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
CD3 Mouse mAb |
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E2220060 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
CD3 Mouse mAb |
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E2220070 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
Anti- Human CD3 |
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Y300161 | ABM | 100 µg | EUR 215 |
CD3 antibody (PE) |
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61R-1195 | Fitzgerald | 100 ug | EUR 340.8 |
Description: Mouse monoclonal CD3 antibody (PE) |
CD3 antibody (PE) |
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61R-1196 | Fitzgerald | 100 ug | EUR 262.8 |
Description: Armenian Hamster monoclonal CD3 antibody (PE) |
CD3 antibody (PE) |
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61R-CD3fCKPE | Fitzgerald | 100 ug | EUR 418.8 |
Description: Mouse monoclonal CD3 antibody (PE) |
CD3 antibody (PE) |
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61R-CD3gHUPE | Fitzgerald | 100 tests | EUR 379.2 |
Description: Mouse monoclonal CD3 antibody (PE) |
Mouse Human CD3 |
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E2790127 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
Mouse Human CD3 |
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E2790128 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
CD3 ζ Antibody |
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E18-5405-1 | EnoGene | 50μg/50μl | EUR 145 |
Description: Available in various conjugation types. |
CD3 ζ Antibody |
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E18-5405-2 | EnoGene | 100μg/100μl | EUR 225 |
Description: Available in various conjugation types. |
CD3 Ab Magbeads |
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E601AB002 | EnoGene | ~2X109 cells, 1ml | EUR 395 |
Description: Available in various conjugation types. |
CD3 antibody (CY5) |
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61R-CD3gHUCY5 | Fitzgerald | 100 tests | EUR 535.2 |
Description: Mouse monoclonal CD3 antibody (CY5) |
CD3 IHC Antibody |
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IW-MA1015 | IHC World | - | EUR 285 |
CD3 Antibody (APC) |
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GWB-2CDBEA | GenWay Biotech | 100 TESTS | Ask for price |
Dog CD3 Antibody |
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GWB-BD4B80 | GenWay Biotech | 2 ml | Ask for price |
Rat CD3 Antibody |
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GWB-43B690 | GenWay Biotech | 0.2 mg | Ask for price |
Rat CD3 Antibody |
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GWB-792CD2 | GenWay Biotech | 0.1 mg | Ask for price |
CD3 Antibody (RPE) |
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GWB-97FEF1 | GenWay Biotech | 100 TESTS | Ask for price |
CD3 Antibody (APC) |
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GWB-C4EF0C | GenWay Biotech | 25 TESTS | Ask for price |
CD3 Antibody (RPE) |
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GWB-CF2370 | GenWay Biotech | 25 TESTS | Ask for price |
Dog CD3 Antibody |
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GWB-Q00922 | GenWay Biotech | 0.1 mg | Ask for price |
CD3 Antibody (RPE) |
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GWB-E2518D | GenWay Biotech | 100 TESTS | Ask for price |
CD3 zeta Antibody |
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abx019047-100ug | Abbexa | 100 ug | EUR 410.4 |
CD3 antibody (FITC) |
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61R-1000 | Fitzgerald | 100 ul | EUR 354 |
Description: Mouse monoclonal CD3 antibody (FITC) |
CD3 antibody (FITC) |
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61R-1032 | Fitzgerald | 100 ug | EUR 282 |
Description: Mouse monoclonal CD3 antibody (FITC) |
CD3 antibody (FITC) |
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61R-1033 | Fitzgerald | 100 ug | EUR 217.2 |
Description: Armenian Hamster monoclonal CD3 antibody (FITC) |
CD3 antibody (FITC) |
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61R-1034 | Fitzgerald | 25 ug | EUR 262.8 |
Description: Mouse monoclonal CD3 antibody (FITC) |
CD3 antibody (FITC) |
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61R-1035 | Fitzgerald | 100 tests | EUR 424.8 |
Description: Mouse monoclonal CD3 antibody (FITC) |
CD3 antibody (FITC) |
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61R-1876 | Fitzgerald | 500 ug | EUR 664.8 |
Description: Mouse monoclonal CD3 antibody (FITC) |
CD3 antibody (FITC) |
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61R-CD3fCKFT | Fitzgerald | 500 ug | EUR 678 |
Description: Mouse monoclonal CD3 antibody (FITC) |
CD3 antibody (FITC) |
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61R-CD3gHUFT | Fitzgerald | 100 tests | EUR 327.6 |
Description: Mouse monoclonal CD3 antibody (FITC) |
CD3 zeta antibody |
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70R-35829 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal CD3 zeta antibody |
When we analyzed correlations between CPRA values obtained from pairs of calculators, we observed that they are significantly and highly correlated. Bland-Altman plots for the comparison between PT-CPRA calculator against the other calculators, show higher differences between PT and CN than between PT and ET and PT and US.
Also, the lowest value for Lin’s concordance coefficient was obtained for the comparison between PT and CN calculators. CPRA values reliability depend on donors’ pool from which it is calculated and it is crucial for classify correctly highly sensitized patients. A CPRA calculator must use donors’ HLA frequencies similar from those who would be actual organ donors.